NHR Science Advanced Immune Support Pack is a comprehensive arsenal of immune-supportive powerful herbs, helping the body maintain a strong defense, and help supports seasonal immune health. The 3 NHR Products that comprise this Advanced Immune Support Pack were selected for their abilities to support the body’s overall immune response, encourage timely immune cell response, and help defend the body in the face of cold-weather challenges.
- Promotes Healthy Immune Response*
- Supports Healthy Inflammatory Response*
- Supports Nose, Throat, & Respiratory Health*
- Supports Seasonal Immune Health*
- Encourages Timely Immune Cell Response*
- Enhances Antioxidant Defense and Helps Inhibit Oxidative Stress*
Andrographis Paniculata has traditionally been used in Indian and Chinese herbal medicine to support seasonal immune health. There are currently 33 published research of randomized controlled trials (7175 patients) either using Andrographis as a monotherapy and as herbal mixture, showing Andrographis to be effective in supporting the body’s overall immune response to help defend the body in the face of cold-weather challenges.
ParActin® is a patented extract from Andrographis paniculata, standardized to 50% andrographolide. ParActin® works by inhibiting NF-kB -- key regulator of the human immune and inflammatory response system. When NFkB is inhibited, pro-inflammatory cytokines and proteins such as COX2, prostaglandins, IL-6, IL-12, INF-γ TNF-α are reduced.
ParActin® also increases the Nrf2-Keap1-ARE (Antioxidant Response Element) pathway, to augment the body’s natural antioxidant enzymes such as heme oxygenase-1, glutathione reductase, glutathione peroxidase, and superoxide dismutase, among others, to help reduce oxidative stress and promote healthy autophagy function.
There are many published studies on the immune-support mechanisms of action of andrographolide: Andrographolide modulate the innate immune response by regulating both classical and alternative activation of macrophages, and regulate specific antibody production, it inhibits a pathogenic agent’s protein synthesis and expression, inhibits it from entering inside the cell wall, inhibits the agent’s DNA replications; reduces the agent’s receptor signaling, & decreases ACE2 expression.
- Promotes Healthy Cortisol Levels*
- Provides comprehensive support for aging immune system*
- Inhibits immune senescence by supporting an already-healthy ratio of naïve-to-memory T cells*
- Promotes youthful immune response by stimulating immune cell development & activity*
- Encourages the body’s first line of defense by promoting natural killer (NK) cell response*
LJ100® is a patented extract from Eurycoma longifolia, standardized to 40% glycol saponins and 22% Eurypeptides. Cortisol is a stress hormone that promotes immunosenescence by inducing a shift from a CD4+ to CD8+ dominant pattern of immunity. In a 2013 randomized placebo controlled study, 63 subjects (32 men, 32 women) with moderate stress were given 200mg of LJ100® or placebo for 4 weeks. LJ100® showed improved overall mood state: Tension (−11%), Anger (−12%), and Confusion (−15%). Stress hormone profile (salivary cortisol and testosterone) was significantly improved by LJ100® supplementation, reduced cortisol exposure (−16%) and increased testosterone status (+37%).
In a 2016 randomized placebo controlled study, 84 middle-aged men & women with low Scoring of Immunological Vigor (SIV) were given 200mg/day of LJ100® for 1 month. LJ100® promotes immunosenescence by significantly improved SIV score, immunological grade, and immunological age by 4 years. The number of total, naïve, CD4+ T cells, and natural killer cells were also significantly increased.
In another study with healthy male recreational athletes, supplementation with LJ100® significantly increased NK cells, supporting immune functions after endurance running in the heat.
- Comprehensive Immune Support*
- Supports Nose, Throat, & Respiratory Health*
- Helps Protect Against Seasonal Immune Challenges*
- Provides Healthy Antioxidant Level*
- Free Radical Scavenger*
Elderberry is primarily found in Europe and North America. Black Elderberries have long been used in traditional cultures to support immune function. Elderberry has an extensive history of being used during seasonal immune challenges. Regarded as an “Elder” plant in Native American Herbalism, Elderberry has been used collectively by many tribes as a tonic medicine and food to promote health and vitality.
In a randomized, double-blind placebo-controlled clinical trial of 312 economy class passengers travelling internationally, supplementation of elderberry supplement encourage timely immune cell response and supports the body to maintain a strong defense during stressful intercontinental air travel.
In another randomized, double-blind, placebo-controlled study during the influenza season of 1999 – 2000 in Norway, 60 volunteers received 15 ml of elderberry or placebo syrup four times a day for 5 days. Supplementation of elderberry help support immune function during seasonal immune challenges.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.