STAY HEALTHY: OPTIMIZE HEALTHY IMMUNE RESPONSE, HELP SUPPORT HEALTHY RESPIRATORY FUNCTION*

NHR Science Advance Immune Support Combo Pack is a comprehensive arsenal of immune-supportive powerful herbs, helping the body maintain a strong defense, and help supports seasonal immune health. Products that comprise in this combo packs were selected for their abilities to support the body’s overall immune response, encourage timely immune cell response, and help defend the body in the face of cold-weather challenges.  The clinically studied ingredients have been shown to provide the following benefits:

• Promotes Healthy Immune & Inflammatory Response*
• Supports Seasonal Immune Health*
• Encourages Timely Immune Cell Response*
• Enhances Antioxidant Defense and Helps Inhibit Oxidative Stress*
• Provides comprehensive support for aging immune system*
• Inhibits immune senescence by supporting healthy cortisol level and healthy ratio of naïve-to-memory T cells* 

Immune 101

Your body’s immune system is your natural protection against harmful invaders.  The Level 1 defense is your natural barriers like your skin that protects you from harmful invaders, and cilia (tiny hairs in your lungs) that brushes out unwelcome intruder so that your body can take them out. 

If Level 1 fails and invaders slips through, Level 2 innate immune defense kicks in.  The innate immunity comprises of a complex network of cells and proteins that defends the body against invaders.  When an invader gets in, your body’s cells and chemicals get on the scene fast – a lot like first responders in real life. They love to fight and they prevent the spread of invaders in the body.

Level 2 innate immune cells and proteins include:

• Defensins send signals for help or fight invaders directly
• Cytokines send signals for help
• Natural killer cells destroy invaders
• Scavenger cells (like neutrophils and macrophages) destroy invaders
• And many other chemicals and cells

 

Level 3 Adaptive or Acquired immunity

CD4+T Cell, CD8+ T Cell, & B Cell are your stored immune memory of past occurrence and are trained to destroy agents quickly if invaders enters the body again.  Antibodies are part of that response and help your body respond to the same invader much faster if you encounter it again.  Some antibodies have a long-lasting effects and are called “memory” antibodies.

Your immune system fights infections using organs, cells and proteins that work together in a highly coordinated dance. Healthy eating, good nutrition, less stress, good sleeping habit and regular physical activity make your immune system stronger and can help you support your immune system. 

Aging & Immune

Aging and other environmental stressors (due to excess inflammation, toxins, and stress) all contribute to a decline in our immune function. As you grow older, your immune system does not work as well, leaving us increasingly susceptible to health threats.   Your body may heal more slowly as there are fewer immune cells in the body to bring about healing.  The immune system's ability to detect and correct cell defects also declines.  In addition, immune cell diversity also declines, reducing our body’s immune defense.  This process is called immune senescence.

The following immune system changes may occur:

1. Decline in Naïve T Cells.  Naïve T cells are inexperience T cells that can easily be activated to recognize and respond to new challenges.  There is a general decrease in naïve T cells after roughly age 70.   As a result, our immune system becomes slower to respond and this increases our risk of getting sick.
2. Increasing Numbers of Senescent Memory T cells. Memory T cells are your stored immune memory of past occurrence that are trained to destroy invaders if they enter the body again.  Our body’s pool of protective memory T cells increase over time.  However, memory T cells from older persons are often senescent, meaning they lost their ability to proliferate and have become dysfunctional.
3. Decreased in Functional Natural Killer (NK) Cell Activity. High NK cell activity is associated with longevity and healthy aging, while reduced NK cell function is linked to increased health imbalances.  NK cell function decreases with age, generating fewer immune-regulating cytokines.
4. Overproduction of Cytokines: Immune senescence is associated with high levels of the inflammatory cytokine interleukin-6 (IL-6).  In the elderly, elevated IL-6 is associated with many health challenges. 

1. Exercise helps boost your immune system.  Regular moderate-intensity exercise can strengthen resistance to invaders and improve immune system function.  Several human studies have indicated that moderate exercise may combat immune senescence.
2. Stress management. Chronic stress diminishes our immune function and dysregulate our innate and adaptive immune responses. Studies had shown cortisol (stress hormone) to contribute to immune senescence.  In fact, the ratio of cortisol to dehydroepiandrosterone (DHEA), may be an important determinant of immune senescence.
3. Sleep deprivation is associated with elevated cortisol levels, as well as higher daytime levels of inflammatory cytokines including IL-1, IL-6, and tumor necrosis factor-alpha.  The adverse effects of poor sleep include functional changes in regulatory T cells and other cells of the adaptive immune system, as well as reduced numbers of NK cells and T and B cells.  Adequate sleep may help improve immune function.
4. Calorie Restriction. The goal of caloric restriction is to reduce total caloric intake while maintaining optimal nutrition. Eat healthy foods primarily composed of low-calorie, nutrient-dense foods such as vegetables, fruits, legumes, nuts and seeds, and whole grains; limiting intake of animal products; and avoiding calorie-dense, nutrient-poor foods.  Calorie restriction in animals has been shown to prolong lifespan and delay aging, and to confer a more youthful T-cell profile.  Good nutrition keeps your immune system strong.
5. DO NOT smoke. Smoking weakens your immune system.
6. Limit your intake of alcohol. Ask your provider how much alcohol is safe for you. 
7. Botanicals such as Andrographis, Eurycoma longifolia, and Elderberry all have studies that can help support your immune health.

 

 *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.